Celaya, Gto., October 11, 2018.- Research on "5-HTTLPR polymorphism, stressful vital events and PHM levels in patients with major depressive disorder" deserved Daniel Vargas Quintana, a graduate student in clinical research, the recognition by the Department of Health of the state of Guanajuato.

Daniel participated in the 25th State Health Research contest and obtained support for the development of a project in mental health. The resources obtained will allow him to boost the study you make to determine the influence of the polymorphism and the stressful vital events that occurred before the age of 15 in the development of psychopathologies such as major depression.

According to the study, stressful life events occurring in childhood can influence the onset and development of symptoms of depression, low resilience, hyperactivity, and decreased ability of individuals to cope with changes and Losses occurring over the course of life.

Some of the factors studied by Daniel Vargas are early traumas that occur due to parental negligence in the care of children, to be witnesses or victims of violent acts in a repeated manner. One of the findings of the research is that these stressful events alter the adrenal pituitary hypothalamic system, causing the effects.

The project also envisages studying the relationship between genetic polymorphism and major depression. It is carried out in patients diagnosed with major depressive disorder who are treated at the psychiatric hospital in León.

According to the World Health Organization, depression is a common mental disorder and of the 350 million people with depression in the world, only 25% of them receive effective treatment. The same organization reports that suicide is the third leading cause of death in young people aged 15 to 24 years and the sixth in children ages 5 to 14. Studies have shown that both conditions are related, and Daniel Vargas will determine if they result from life experiences or genetic factors.

In Mexico, studies conducted by the National Survey of Psychiatric Epidemiology showed that 2.0% of the Mexican population has suffered an episode of major depression before the age of 18. The Mexican Adolescent Mental Health survey in Mexico City reported that 10.5% of adolescents between 12 and 17 years had major depression, persistent depressive disorder and bipolar I and II disorder, which makes this research.

The professor of the Celaya-Salvatierra Campus, Dr. Herlinda Aguilar Zavala, accompanies Daniel Vargas Quintana in the development of the study, which began in 2017 and will be extended to 2019, according to reported.

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